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Varol, L

The second meta-analysis in 77,485 people from 28 randomized clinical trials showed that in people with type 2 diabetes, overweight, and obesity, treatment with GLP-1 receptor agonists was associated with a significant reduction of 14% in the relative risk, while separate medications, semaglutide, liraglutide, and dulaglutide, were associated with a reduction in the relative risk of 18%, 14%, and 18% for overall respiratory disease

[DOI] [PubMed] [Google Scholar] 62.Falken Y, Hellstrom PM, Holst JJ, Naslund E

Pharmacokinetic Advantages Orforglipron's pharmacokinetic profile represents a decisive advance over all existing oral GLP-1 formulations and, in several respects, confers advantages even over injectable GLP-1 receptor agonists

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