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Therapeutic significance of pyroptosis in IRI-AKI Although gasdermins and pyroptosis are not yet fully understood, they are thought to have a significant impact on tissue homeostasis, inflammation, and the development of various diseases

Concurrently, a Phase 2 trial (NCT06603571) is ongoing to evaluate eloralintide in combination with tirzepatide, assessing safety, tolerability, and enhanced weight loss effects

These findings suggest that UB might significantly contribute to improving the prognosis for CRC patients, offering novel avenues for CRC therapy and prevention

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