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Since it is abundant in hypothalamus, it can affect the neuronal activity and thus hypothalamo-pituitary gonadal (HPG) axis to exert its impact on female reproduction [16]

The majority of users who report gastrointestinal side effects reported that they are dose-dependent [7]
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Acetyl-L-carnitine is neuroprotective when administered at supraphysiological concentration [114]

HepG2 cells showed an approximately 8% increase in survival after 48 h of exposure to C16-carnitine, whereas HT29 and HCT 116 cells exhibited reduced survival [67]
