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10.1038/s41419-024-07166-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Alexandre-Santos B., Alves R., Matsuura C., Sepulveda-Fragoso V., Velasco L

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By targeting opioid receptors in the central nervous system, dynorphin analogues can modulate pain perception and provide relief from acute and chronic pain conditions

and i.g., respectively) either within 10 days preceding 3 months of alcohol consumption (prophylactic), simultaneously during the entire alcohol drinking period, or throughout the last month of the drinking