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FIGURE 1 The diagnosis of SJS was established based on the skin and mucosal involvement and positive Nicolskys sign

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However, neurologically significant deficiency may occur with low-"normal" serum levels

You should not get a B12 injection if you are allergic to cyanocobalamin (vitamin B12)

continuation beyond three to six months depends on symptomatic benefit and laboratory confirmation of necessity, and therapy may be indefinite when tolerated and beneficial

143,144 The mutated IDH1 and IDH2 proteins are endowed with a novel ability to catalyze the reduction of -KG to generate a rare metabolite, 2-hydroxyglutarate (2-HG), while consuming NADPH