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Step-by-step sublingual administration technique Step 1: Prepare the oral environment

5.1 Genetic mechanisms of riboflavin transport and utilization defects Dietary riboflavin bioavailability depends on coordinated processes including intestinal absorption, cellular uptake, intracellular activation, and mitochondrial transport

2h and Extended Data Fig

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C-MET927-LZ c-MET (amino acids 1927) followed by a GGGGS linker, a GCN4 zipper sequence (RMKQL EDKVE ELLSK NYHLE NEVAR LKKLV GER), HR3C, Tsi3 tag, and His6 tag, was cloned into the pEZT-BM vector (Supplementary Table 1)