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It was also shown that mice with overexpression of dominant-negative PKD1 exhibited decreases running performance and significantly impaired voluntary running-induced myofiber transformation in skeletal muscle, which confirms that PKD1 plays a crucial role in skeletal muscle remodeling upon physical training [173]

[DOI] [PMC free article] [PubMed] [Google Scholar] 249.Sajic, M

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al

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Reduced levels of L-carnitine would be expected to have a similar effect as they could equally result in an inability to transport fatty acids into the mitochondria for oxidation

BARRINGER, SARAH L., APO San Francisco