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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Sikiric P., Udovicic M., Barisic I., Balenovic D., Zivanovic Posilovic G., Strinic D., Uzun S., Sikiric S., Krezic I., Zizek H., et al

One unit (1 U) of enzyme activity is defined as 1 mol of product (DCPIP red or ubiquinone-Q1 red ) formed per minute

PMID: 28267766

Since each of the tested reducing agents/thiols blocked melanin production, it is conceivable that accumulation of thiols directly upstream of Gsh2 (-Glu-Cys and cysteine) could contribute to the enhanced redox buffering and/or lack of melanin in gsh2 mutants, likely through diversion to other metabolic pathways

Thus, NFT formation may be considered a more reliable diagnostic parameter to judge the clinical severity of AD than amyloid plaque formation (Giannakopoulos et al

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