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Andreeff M , Kreis W, Miller W, Gee T, Berman E, Kolitz J, Kempin S, Straus D, Reich A, Tafuri A, Espiritu E, Deere M, Clarkson B

A wide diversity of microbial resources provides by nature, microbes have more adaptation abilities and inhospitable atmospheres like Dead Sea, Antarctica, Alkaline lakes, Hot springs, volcanic vents and contaminated soils, which provides extraordinary potential for the lipases production with specific features [104, 105]

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In addition, melatonin showed a variety of regulatory effects on sexual behavior, immune function, energy metabolism, the cardiovascular system, the reproductive system, and the neuropsychiatric system [4,7]