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Why ARA-290 Is Different from Erythropoietin Erythropoietin: Increases red blood cell production Raises hematocrit Increases thrombosis risk at high levels ARA-290: Does not affect red blood cells Does not raise hematocrit Does not increase clotting risk This distinction makes ARA-290 suitable for chronic use in inflammatory and neurologic conditions , where EPO would be unsafe

Dosing Example: To get that same 1mg dose, you would now draw 0.2 mL (or 20 units)

A random RNAi was the negative control

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Discard if cloudy or discolored

Suggested Typical Dosage: Inject 1ML Intramuscularly, twice a week