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Interestingly, recent trials concluded the antiviral activity of chloroquine against COVID-19 (88), where they suggested that chloroquine has increased flux of zinc into the cell (89)
Monomeric -synuclein induces bloodbrain barrier dysfunction through activated brain pericytes releasing inflammatory mediators in vitro
Likewise, a positive cell-based assay or preclinical model result cannot be used as a substitute for validated clinical evidence
1 That selectivity became the compounds defining feature
Her case was exceptional in that she felt improvement so dramatically and quickly
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