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Even in small amounts vitamin C can protect indispensable molecules in the body, such as proteins, lipids (fats), carbohydrates, and nucleic acids (DNA and RNA), from damage by free radicals and reactive oxygen species (ROS) that are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherapy drugs and cigarette smoke)

That decline correlates with slower wound healing, thinner skin, and reduced regenerative capacity

In summary, the structural characteristics of NRF2 highlight its multifunctional and intricated regulatory role in cellular stress responses

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Peripheral glial cells in the development of diabetic neuropathy