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A therapeutic dose is the amount of a medication required to achieve the desired clinical effect without causing significant side effects

Endocr Connect

Rapid or excessive weight loss is generally not healthy or sustainable

Evidence for Benefits Aging and Oxidative Stress Glutathione depletion is a consistent finding in aging research

2021 Jun Pietro Ghezzi, Kevin V Lemley, James P Andrus, Stephen C De Rosa, Arne Holmgren, Dean Jones, Farook Jahoor, Richard Kopke, Ian Cotgreave, Teodoro Bottiglieri, Neil Kaplowitz, Hajime Nakamura, Frank Staal, Stephen W Ela, Kondala R Atkuri, Rabindra Tirouvanziam, Kartoosh Heydari, Bita Sahaf, Andrew Zolopa, Richard Eugene Frye, John J Mantovani, Leonard A Herzenberg, Leonore A Herzenberg

This indicated that testicular development may be only partly GH-dependent, with the majority of stimulatory effects on testes mediated directly by IGF (88)