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demonstrated mitochondrial ribosomal protein CRIF1 deficiency leads to a negative environment for T lymphocytes, which results in T cell exhaustion due to elevated reactive oxygen species and lactate production in liver cancer progression [137]
FEV1: 84, FVC: 78, Total Lung Capacity: 78, Diffusing Capacity: 92 This 33-year-old man presents with progressive exertional dyspnea, severe obesity (BMI 46 kg/m), and a normal pulmonary examination without evidence of intrinsic lung disease

Antiangiogenic agents in the treatment of recurrent or newly diagnosed glioblastoma: analysis of single-agent and combined modality approaches

Kopple 2010

Jiang HP, Serrero G
