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Journal of Clinical and Aesthetic Dermatology
The last expiry date of these follow-on patents is November 22, 2040, 14 years after the expiration of the 208 patent covering the original compound
The stimulating effects of caffeine come from blocking adenosine receptors in the brain
Every puncture introduces a small risk of contamination, and 28 days represents a conservative but scientifically supported window for multi-dose use
doi: 10.1016/j.pharep.2015.03.002
