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It also reduces the secretion of transforming growth factor-beta1 in fibroblasts, an important step in countering the negative effects of DHT

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While adequate and well-controlled studies specifically in pregnant women are limited, vitamin B12 is essential, and its requirements increase during pregnancy
This selectivity, combined with its ability to efficiently cross cellular membranes, makes it an invaluable research tool for dissecting the specific contributions of NNMT to metabolic regulation

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