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Patients seeking moderate weight loss (10-15% body weight): Orforglipron's Phase 3 data show mean weight loss of approximately 11% at 72 weeks, with about 55% of participants achieving 10% or greater loss

PMID 25195560

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But because unexplained hypercobalaminemia has been consistently associated with an elevated risk of subsequent cancer diagnosis in large population studies, its one of those lab results worth following up on rather than hoping it goes away

After that, many patients shift to monthly doses for maintenance

While B-12 is typically found in foods like meat, dairy, and eggs, some individuals may have difficulty absorbing it through their digestive system