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Neuropsychopharmacology 37, 16471655 (2012)

This process causes its oligomerization and accumulation in the form of senile plaques in the brain cortex, hippocampus, and other brain areas

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(2003) Recent advances in the prediction of blood-brain partitioning from molecular structure

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On the other hand, very few intranasally delivered large molecules are commercialized to treat CNS disorders
