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doi: 10.1016/S0925-4439(00)00018-1
Chin Med J (Engl) 114(2):152154 Fu Y, Liu X, Chen N, Zhang S, Chang H, Zhang Q, Chen X, Gao X (2013) Signal transduction pathways of Toll-like receptors 3 and 4 in peripheral blood mononuclear cells from patients with purpura nephritis

This leads to considerable variability in results across laboratories, which hampers reproducibility in large-scale studies and clinical applications

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The RTC contains papain-like protease NSP3, protease NSP5, primase complex NSP7NSP8, RNA-dependent RNA polymerase NSP12, helicase/triphosphatase NSP13, exoribonuclease NSP14, endonuclease NSP15, and methyltransferases NSP10NSP16 1,42

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