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Indeed, the removal of glutamine from the media significantly decreased AML cell growth in a concentration-dependent manner ( Supplementary Figure S1E )

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doi: 10.1016/0168-8278(89)90083-4

The rate-limiting component in the biosynthesis of glutathione is the availability of cysteine

Key handling errors that can cause problems include: Shaking the vial vigorously during reconstitution, which denatures the peptide Using sterile water instead of bacteriostatic water, which lacks preservatives and allows bacterial growth Storing reconstituted peptide at room temperature instead of refrigerated Leaving the vial exposed to light, which degrades photosensitive amino acids Using reconstituted peptide beyond its stability window, typically 3-4 weeks Properly handled AOD 9604 should be clear and colorless in solution