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Insulin-like growth factor-1 and carbohydrate metabolism IGF-1 can promote glucose uptake in certain peripheral tissues [137140] in the magnitude of 47 % from that of insulin [141, 142]

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The fact that vitamin C supplementation alone did not affect molecules indicative of oxidative stress, including reactive oxygen species (ROS), superoxide dismutase (SOD), and malondialdehyde (MDA), may support the more beneficial use of vitamins C and E together [32]

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Inhibition of the Trx system by auranofin induced cell death (most likely ferroptosis) only in non-endocrine small cell lung cancer, whereas inhibition of the Grx system by buthionine sulfoximine killed specifically the endocrine cells [203]