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One significant limitation of GHK-Cu is its short in vivo half-life of approximately 30 minutes in plasma, combined with the instability of the metal-peptide complex due to copper high reactivity

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extracellular matrix glycoproteins, molecules that form the framework of tissues and participate in their restoration and hydration

[14] There is not enough data to guarantee safety for the fetus or nursing infant

Protoplasma 251:13731386 Munsif F, Kong X, Khan A, Shah T, Arif M, Jahangir M, Akhtar K, Tang D, Zheng J, Liao X (2021) Identification of differentially expressed genes and pathways in isonuclear kenaf genotypes under salt stress

[DOI] [PubMed] [Google Scholar] 83.Nabi T., Nabi S., Rafiq N., Shah A