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[DOI] [PubMed] [Google Scholar] 138.Lundgren O 5-Hydroxytryptamine, enterotoxins, and intestinal fluid secretion
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In vitro , butyrate increased the expression of mitogen-activated protein kinase phosphatase-1 (MKP-1), which dephosphorylates activated c-Jun N-terminal kinase (JNK), ERK1/2, and p38 Mitogen-activated protein kinase (MAPK) to counteract excessive inflammation in RAW264.7 macrophages (214)

Slow digestion can affect nutrient absorption from food, leading to low energy levels over time
