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[DOI] [PubMed] [Google Scholar] 255.Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL

Drug Metab Dispos 1992, 20: 374-378

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107 showed that the p K a of lipids or lipidoids is of great importance for delivering siRNA to hepatocytes in vivo