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In an in-vitro study of H9C2 cardiomyocytes, melatonin treatment increased Notch1, Notch1 intracellular domain, BCL-2, and Hes1 expression and the ratio of phosphorylated to unphosphorylated Akt, while reducing caspase-3, PTEN, and BAX expression [24]

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doi:10.3389/fphar.2019.00694 Nattagh-Eshtivani E, Gheflati A, Barghchi H, et al

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However, NGS did not detect any mixed genotypes but identified genotype 2i for specimen M51 and genotype 3a for specimen M54 in both target regions, respectively