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The disease is spontaneous, is associated with a relatively low frequency within the colony and lesions that wax and wane, making it an interesting observation but not a model that is readily amenable to experimental manipulation

Long-term exposure to CR can reduce not only oxidative stress but also the oxidative damage of the mitochondrial DNA (by 30%)

Endothelial dysfunction is closely linked to hypertension, which further accelerates cardiovascular complications (Drod et al

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Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration

Novel immunological and genetic factors associated with vitiligo: A review