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Furthermore, ligands derived from the hexapeptide Ang IV but that are not proven to act as IRAP inhibitors have been reported

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These compounds work through independent mechanisms, meaning they can potentially be used together under physician supervision without pharmacological conflict

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Five out of six of these peptides (all but GHK-Cu) are currently in something called Category 2, which means compounding is not allowed for them due to risks or limited data

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