glutathione reducate biosensor Reductase - an overview A Selective Glutathione Probe based

Deficiency in B6 results in impairment of the cystathionine -synthase and cystathionine lyase catalyzed reactions, both of which require B6 (pyridoxal phosphate, PLP) as cofactor

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doi: 10.1001/jama.2022.23661 28 HolingueC.NewillC.LeeL

Fulton DJR, Li X, Bordan Z, Wang Y, Mahboubi K, Rudic RD, et al

Thiamine is not stored to any appreciable extent in the body and amounts in excess of the bodys requirements are excreted in the urine as unchanged thiamine or as metabolites

Physiological phases like lactation or pregnancy gave no statistically significant differences (Figure 1a) (Supplementary Table S3)