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In synthesis, environmental factors in pain are multifactorial, ranging from discrete physical and iatrogenic injuries that directly damage tissues and nerves, to broader contextual exposures that alter systemic physiology and neural processing

Vitamin D deficiency during lung development can lead to structural abnormalities and impaired lung function [342,343,344,345,346]

Pinkosky, S

In the analysis of ferroptosis-related genes in patients with UC, 26 differentially expressed genes have been identified that are significantly enriched in energy pathways and metabolism, with the top 10 hub genes from the protein-protein interaction network as interleukin 6 (IL6), prostaglandin-endoperoxide synthase 2 (PTGS2), hypoxia inducible factor 1 alpha (HIF1A), cluster of differentiation 44 (CD44), mucin 1 (MUC1), caveolin 1 (CAV1), nitric oxide synthase 2 (NOS2), C-X-C motif chemokine ligand 2 (CXCL2), stearoyl-CoA desaturase (SCD), and acyl-CoA synthetase long chain family member 4 (ACSL4) (62)

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Helps maintain energy metabolism and vitality