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To simulate the progression of AS in vitro, aortic rings were treated with PCSK9 protein (1000 ng/ml

Correspondingly, the inhibition of NF-B by BAY 11-7082 significantly increased the survived SGN numbers, while decreased the C-CASP3 positive SGN numbers and the C-CASP3 expression in peroxynitrite + BAY 11-7082 group compared with the peroxynitrite group (Figures 9DF)

High glucose and erastin significantly induce LDH release, promote the expression of ACSL4, cyclooxygenase 2, and NADPH oxidase 1, and decrease GPX4 levels

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T.et al (2014)