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6) Design Space: A range of acceptable values for the CMAs and CPPs within which the desired CQAs are consistently achieved are defined

doi: 10.1038/s41423-021-00726-4, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 76

Engineering the luxCDABE genes from Photorhabdus luminescens to provide a bioluminescent reporter for constitutive and promoter probe plasmids and mini-Tn5 constructs

The relative expression levels of target genes were assessed using SYBR Green-based quantitative PCR performed on a Bio-Rad CFX96 real-time PCR detection system

Introduction Neurological injury and chronic stress are important factors in the pathophysiology of depression (Lazaratou et al., 2010)

however, the current delivery systems struggle to achieve precise targeting, negatively influencing therapeutic outcomes and increasing systemic adverse effects