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In urethane-anesthetized female Wistar rats, L-theanine could reduce substance P-induced bladder hyperfunction through inhibiting pro-inflammatory protein kinase C (PKC)/ERK/NF-B/intercellular adhesion molecule 1 (ICAM-1)/IL-33 signaling, oxidative stress, apoptosis, autophagy (99)
Cell lines were selected with 1 g/ml puromycin for 3 d

It has been suggested that excess copper may increase the free radical content and aggravate the occurrence of diseases such as aging and malignancy

The PI3K inhibitor 3-methyladenine blocked the formation of autophagosomes, increased the lipid content of hepatocytes and promoted the formation of MASLD (89)

water for injection q.s
