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[DOI] [PMC free article] [PubMed] [Google Scholar] 250.Wu W., Sung C.C., Yu P., Li J., Chung K.K.K

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Abstract Introduction Peptides occupy a strategic position between small molecules and biologics, offering high target specificity, favourable safety profiles, and chemical tractability
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Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice

First, these data suggest that it is the presence of excess APP expression, not the mutant PSEN1, that is the most likely driver of myelin abnormalities
