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Overall, ketogenic diet and exogenous ketones represent a rapidly translatable set of interventions with strong biological plausibility and some clinical proof of concept data to support investigation in both aging and military-relevant resilience and rehabilitation contexts particularly involving cognitive resilience, traumatic brain injury, and maintenance and recovery of muscle function through serious damage and/or illness

In a short study of healthy older people, therapy with the glutathione-boosting supplement glyNAC for 24 weeks resulted in lower levels of inflammation

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Furthermore, the kynurenine/tryptophan ratio was markedly diminished in the tumors from the JHU083-treated mice (Figure 11E)

Ethics declarations Competing interest The authors declare that there is no conflict of interest