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2012 Dec;130(6):e1447-54

For the past 60 years, reactive oxygen species and iron-dependent lipid peroxidation (LPO) have been hypothesized to be involved in many models of acute drug-induced liver injury

Autophagy, particularly through peroxisomal and mitochondrial autophagy, is instrumental in neutralizing ROS and safeguarding cells from oxidative stress

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