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Positive Regulation of Interleukin-1 Beta Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation

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We thank the technical services provided by the Synchrotron Radiation Protein Crystallography Facility of the National Core Facility Program for Biotechnology, Ministry of Science and Technology and the National Synchrotron Radiation Research Center, a national user facility supported by the Ministry of Science and Technology, Taiwan, ROC

Sustained systemic glucocerebrosidase inhibition induces Brain -synuclein aggregation, microglia and complement C1q activation in mice

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Developed in the laboratory of Joseph Harding at Washington State University as part of a program optimizing angiotensin-IV-derived neurotrophic peptides, Dihexa is approximately seven orders of magnitude (~10,000,000-fold) more potent than BDNF in inducing functional synaptogenesis between hippocampal neurons in vitro a figure that, even discounted aggressively, places it in a category of its own