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Description
doi: 10.1016/j.cell.2004.12.041

Yes, if used in recommended amounts and followed by sunscreen
Both are once-weekly injections
Side effects of Berberine, such as constipation, diarrhea, and flatulence, are uncommon

Nat Rev Endocrinol 13:220231

Arginase signalling as a key player in chronic wound pathophysiology and healing