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Description
International Journal of Molecular Sciences
That approach may be coming to an end

The deregulation of TET enzymes also affects the pluripotency and differentiation of embryonic stem cells, with oncogenic signaling interfering with lineage-specific differentiation programs (135)
Specifically, it can lead to major birth defects of the brain and spine called neural tube defects (NTD)

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

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