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This intermediate is responsible for cyclization, hydrolysis, and base-exchange reactions 133

10.1016/j.isci.2023.108248

5 Therapeutic effects and mechanisms of APS on neurodegenerative diseases The prevalence and incidence of neurodegenerative diseases increase sharply with age (Checkoway et al., 2011)

For instance, antispasmodic drugs (mainly anticholinergics) and antidiarrheal agents are used for abdominal pain and diarrhea

It also improves skin textures, lightens hyperpigmentation and skin blemishes

It is characterized by memory loss, language difficulty, impaired judgment, mood swings and, in advanced stages, loss of self-care ability (1)