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Ringed sideroblasts and increased iron stores are usually present

Structures of CaV2 Ca 2+ /CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation

Moreover, LA treatment prevents the inhibition of connective tissue hyperplasia in mouse liver injuries caused by the normal diet administration with high n-3 PUFAs content for 8 weeks

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In glioblastoma, ferroptosis presents a unique vulnerability, as tumor cells exhibit ferroaddiction, an increased dependence on iron (Fe 2+ ) for metabolic functions, yet simultaneously deploy protective mechanisms to evade ferroptotic cell death (Fig