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Phentermine is not appropriate for patients with: Coronary heart disease, congestive heart failure, heart rhythm problems, or a history of stroke Uncontrolled high blood pressure Untreated thyroid problems (hyperthyroidism) Pulmonary hypertension Untreated glaucoma Use of an MAO inhibitor (a class of antidepressants) within the last 14 days including rasagiline, tranylcypromine, selegiline, phenelzine, linezolid, and isocarboxazid Can I start phentermine at the highest dose

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Despite early promise, it has not been approved by major regulatory bodies like the FDA for therapeutic use in humans
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