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Their function is closely associated with lipid uptake and accumulation, a mechanism that enhances their immunosuppressive phenotype [241]

Am J stem cells 7(5):104 Baumann M (2016) CRISPR/Cas9 genome editingnew and old ethical issues arising from a revolutionary technology

The PDE4 inhibitor roflumilast is an approved drug that selectively inhibits PDE4 and increases cAMP levels, leading to an anti-inflammatory response

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NeuroReport 9 , 367372 (1998)

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