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218 In another placebo-controlled trial in 48 subjects who were overweight or obese, 1,000 mg pomegranate extract for 30 days reduced inflammatory marker levels and improved blood glucose, insulin, and LDL-cholesterol levels

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Immunobiol 214:339 Martin D, Rojo AI, Salinas M, Diaz R, Gallardo G, Alam J, De Galarreta CM, Cuadrado A (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

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Unlike SLC25A1 inhibitors that remain in the preclinical research stage, the ACLY inhibitor bempedoic acid has been approved by the FDA as a new lipid-lowering drug