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Protein restriction may contribute to perturbations in cellular protein homeostasis, resulting in GCN2-mediated, ATF4-dependent activation of FGF21 expression (84)

As a result of its unique ability to distinguish changes in exact sites in the protein sequence (Larsen et al., 2006), MS/MS has become especially vital in post-translational modification studies

[15] Whatever the cause, it is known that B-12 deficiency causes neuropathies, even if folic acid is present in good supply, and therefore anemia is not present

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SIRT is an intra-arterial brachytherapy primarily used to treat hepatocarcinoma and hepatic metastases, however its use in ICC is not as widespread3,4