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The applicability of these technologies has been demonstrated by approvals of ADCs (e.g., trastuzumab emtansine in 2013, trastuzumab deruxtecan in 2019, and sacituzumab govitecan in 2020), the first BiTE (blinatumomab in 2014), and the first nanobody (caplacizumab in 2019)

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This distinction matters because KPV is also sold online as a "research chemical" by unregulated vendors, and the quality gap between those products and pharmacy-grade KPV is significant

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Because all B vitamins are water soluble, the body is incapable of storing them
