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Reppert SM

The subsequent reaction forming EGT is catalyzed by Egt2

McQueen, Elsevier, Oxford, 2010, Volume 4, Pages 323366

In response to neuronal injury caused by excitotoxicity, astrocytes can generate and release cytokines such as IL-1, IL-6, tumor necrosis factor (TNF)-, transforming growth factor (TGF)-, monocyte chemoattractant protein-1 (MCP-1), and chemokine C-motif ligand 2 (CCL2

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Various delivery systems have been developed to enhance their efficacy and overcome limitations, as summarized in Table II with the overall goal of restoring visual clarity