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Effect of mROS on Tumor Immune Environment The control of mitochondria-derived ROS has been increasingly explored as a driver of the recruitment and the activation of immune cells in tumor environment
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doi: 10.1523/JNEUROSCI.5922-09.2010

The gene expression of glutathione peroxidases was found to be comparable between influenza-infected and control mice, in contradistinction to glutathione reductase (Figures E2A and E2B)
Although less rigorous, clinical series in humans suggests the same with a smaller percentage of side effects with hydroxychloroquine compared to chloroquine when the two are given in comparable dosages [137, 138]