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Sleep disruption increases neuroinflammation, especially in the hippocampus, with chronic sleep disruptions worsening inflammatory responses in the brain (40, 58, 59)

The presence of oligopeptides from protein digestion in the stomach stimulates gastrin release, which enhances LES constriction (Reference Zeng, Ou and Wang81Reference Soll and Walsh83)

10.1371/journal.pone.0019338 87 MasudaM.SuzukiN.TaniguchiS.OikawaT.NonakaT.IwatsuboT.et al

Increased ROS levels can activate NF-B and MAPK, and then activate psoriasis Th1 and Th17 cells (134)

Increased Longevity: NAD+ plays a role in maintaining cellular health, and studies show it can help increase lifespan

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