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The treatment reduced the opacity levels in the cataracts of the rats by inhibiting the Ca2+ upregulation, which is related to selenite-induced nuclear cataract formation (151)

In addition, epithalon delivered by injection may occasionally cause inflammatory reactions surrounding the injection site

Lieu YK, Hsu BY, Price WA, Corkey BE, Stanley CA
Pemmaraju N, Carter B, Kantarjian H, Cortes J, Bose P, Kadia T, Garcia-Manero G, Bueso-Ramos C, DiNardo C, Bledsoe S, Daver N, Popat U, Konopleva M, Ohanian M, Pierce S, Zhou L, Estrov Z, Borthakur G , Mak PY, Jain N, Jabbour E, Verstovsek S
Vicente P, Almeida JI, Crespo IE, Virgolini N, Isidro IA, Calleja-Cervantes ME, Rodriguez-Madoz JR, Prosper F, Alves PM, Serra M (2024) Oxygen control in bioreactor drives high yield production of functional hiPSC-like hepatocytes for advanced liver disease modelling

Some studies suggest that very long-term use (years of high doses) could potentially lower zinc levels