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On MRI pleomorphic liposarcomas are difficult to differentiate from other aggressive sarcomas because they present as heterogeneous masses (low on T1WI, high on T2WI, with heterogeneous enhancement) and because they contain little or no fat

There is insufficient evidence to determine whether NAD+ supplementation influences glucose homeostasis in clinically meaningful ways, but patients should maintain regular glucose monitoring as recommended by their healthcare provider

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Even though the binding pocket of the NTD is less occluded, cholesterol seems to bind 1.0 deeper compared with the NTD from hNPC1 (Fig S7B)

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Greenfield JM, Shah SJ, Levine LA